BDBM50131274 3-Amino-N-(3-{4-[3-(7-chloro-quinolin-4-ylamino)-propyl]-piperazin-1-yl}-propyl)-N-cyclopropylmethyl-propionamide::CHEMBL90430

SMILES NCCC(=O)N(CCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)CC1CC1

InChI Key InChIKey=FCVSDODCADLIIN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131274   

TargetAminopeptidase N(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50131274(3-Amino-N-(3-{4-[3-(7-chloro-quinolin-4-ylamino)-p...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibitory activity against mammalian Aminopeptidase N (APN)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetM1 family aminopeptidase(Plasmodium falciparum (isolate FcB1 / Columbia))
University of Lille

Curated by ChEMBL
LigandPNGBDBM50131274(3-Amino-N-(3-{4-[3-(7-chloro-quinolin-4-ylamino)-p...)
Affinity DataIC50: 2.10E+4nMAssay Description:Inhibitory activity for Plasmodium falciparum Zinc aminopeptidaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetAminopeptidase N(Pig)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50131274(3-Amino-N-(3-{4-[3-(7-chloro-quinolin-4-ylamino)-p...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of porcine kidney aminopeptidase N using Leu-pNA as substrate by microplate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed