BDBM50131469 (S)-22-Chloro-11-cyclohexyl-18-oxa-3,9,12,15-tetraaza-tricyclo[17.4.0.0*5,9*]tricosa-1(19),20,22-triene-4,10,13,16-tetraone::CHEMBL2204325

SMILES [H][C@@]12CCCN1C(=O)[C@H](NC(=O)CNC(=O)COc1ccc(Cl)cc1CNC2=O)C1CCCCC1

InChI Key InChIKey=XZWIFDZVMQYDHZ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131469   

TargetTissue-type plasminogen activator(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131469((S)-22-Chloro-11-cyclohexyl-18-oxa-3,9,12,15-tetra...)
Affinity DataKi:  9.30E+3nMAssay Description:Inhibitory activity against Tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131469((S)-22-Chloro-11-cyclohexyl-18-oxa-3,9,12,15-tetra...)
Affinity DataKi:  9.30E+3nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131469((S)-22-Chloro-11-cyclohexyl-18-oxa-3,9,12,15-tetra...)
Affinity DataKi:  9.30E+3nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed