BDBM50131474 (S)-20-Benzyl-25-chloro-1,4,13,18,21,23-hexaaza-tricyclo[20.3.1.0*6,11*]hexacosa-6(11),7,9,22,24-pentaene-3,26-dione::CHEMBL329912

SMILES Clc1cnc2N[C@@H](Cc3ccccc3)CNCCCCNCc3ccccc3CNC(=O)Cn1c2=O

InChI Key InChIKey=XYHOPCIUIJZGAQ-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131474   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131474((S)-20-Benzyl-25-chloro-1,4,13,18,21,23-hexaaza-tr...)
Affinity DataKi:  0.510nMAssay Description:Inhibitory activity against thrombin IIaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131474((S)-20-Benzyl-25-chloro-1,4,13,18,21,23-hexaaza-tr...)
Affinity DataKi:  4.10E+4nMAssay Description:Inhibitory activity against human trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed
TargetTissue-type plasminogen activator(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50131474((S)-20-Benzyl-25-chloro-1,4,13,18,21,23-hexaaza-tr...)
Affinity DataKi:  1.65E+5nMAssay Description:Inhibitory activity against Tissue plasminogen activatorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/8/2012
Entry Details Article
PubMed