BDBM50131565 2-[4-(2,4-Diamino-quinazolin-6-ylmethoxycarbonyl)-benzoylamino]-pentanedioic acid::CHEMBL119161

SMILES Nc1nc(N)c2cc(COC(=O)c3ccc(cc3)C(=O)N[C@H](CCC(O)=O)C(O)=O)ccc2n1

InChI Key InChIKey=ZNUDIEOBFLPDJF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131565   

TargetDihydrofolate reductase(Rat)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50131565(2-[4-(2,4-Diamino-quinazolin-6-ylmethoxycarbonyl)-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of rat liver Dihydrofolate reductase (rlDHFR)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed