BDBM50131585 4-Chloro-5-(4-ethoxy-phenyl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole::CHEMBL324509

SMILES CCOc1ccc(cc1)-c1c(Cl)ncn1-c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=XPGDSOZXGGQUBM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131585   

TargetProstaglandin G/H synthase 2(Human)
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131585(4-Chloro-5-(4-ethoxy-phenyl)-1-(4-methanesulfonyl-...)
Affinity DataIC50: 4nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131585(4-Chloro-5-(4-ethoxy-phenyl)-1-(4-methanesulfonyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed