BDBM50131621 4-Chloro-5-(2,3-dihydro-benzofuran-5-yl)-1-(4-methanesulfonyl-phenyl)-1H-imidazole::CHEMBL325894

SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccc2OCCc2c1

InChI Key InChIKey=MSZINACGMWACHB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131621   

TargetProstaglandin G/H synthase 2(Human)
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131621(4-Chloro-5-(2,3-dihydro-benzofuran-5-yl)-1-(4-meth...)
Affinity DataIC50: 9nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131621(4-Chloro-5-(2,3-dihydro-benzofuran-5-yl)-1-(4-meth...)
Affinity DataIC50: 110nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed