BDBM50131646 4-[4-Chloro-5-(3-chloro-4-methoxy-phenyl)-imidazol-1-yl]-benzenesulfonamide::CHEMBL115979

SMILES COc1ccc(cc1Cl)-c1c(Cl)ncn1-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=YJVDVVFPGPAHQX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131646   

TargetProstaglandin G/H synthase 2(Human)
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131646(4-[4-Chloro-5-(3-chloro-4-methoxy-phenyl)-imidazol...)
Affinity DataIC50: 5nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131646(4-[4-Chloro-5-(3-chloro-4-methoxy-phenyl)-imidazol...)
Affinity DataIC50: 1.20E+3nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed