BDBM50131660 CHEMBL118497::Succinic acid mono-[4-hydroxycarbamoyl-2-(4-phenoxy-benzoylamino)-pentyl] ester

SMILES C[C@@H](C[C@@H](COC(=O)CCC(O)=O)NC(=O)c1ccc(Oc2ccccc2)cc1)C(=O)NO

InChI Key InChIKey=STDLDNSJNOVMBK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131660   

Target72 kDa type IV collagenase(Human)
National Cardiovascular Center Research Institute

Curated by ChEMBL
LigandPNGBDBM50131660(Succinic acid mono-[4-hydroxycarbamoyl-2-(4-phenox...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human Matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMacrophage metalloelastase(Human)
National Cardiovascular Center Research Institute

Curated by ChEMBL
LigandPNGBDBM50131660(Succinic acid mono-[4-hydroxycarbamoyl-2-(4-phenox...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human Matrix metalloprotease-12 (MMP-12)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
National Cardiovascular Center Research Institute

Curated by ChEMBL
LigandPNGBDBM50131660(Succinic acid mono-[4-hydroxycarbamoyl-2-(4-phenox...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human Matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed