BDBM50131664 CHEMBL326489::N*4*-Hydroxy-N*1*-{1-[(methoxy-phenyl-methyl)-carbamoyl]-2,2-dimethyl-propyl}-2-[3-(2-methyl-biphenyl-4-yl)-propyl]-succinamide

SMILES CO[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCc1ccc(c(C)c1)-c1ccccc1)CC(=O)NO)C(C)(C)C)c1ccccc1

InChI Key InChIKey=MDNBGABATBOAOY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50131664   

TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50131664(N*4*-Hydroxy-N*1*-{1-[(methoxy-phenyl-methyl)-carb...)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of human matrix metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50131664(N*4*-Hydroxy-N*1*-{1-[(methoxy-phenyl-methyl)-carb...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human matrix metalloprotease-9 (MMP-9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50131664(N*4*-Hydroxy-N*1*-{1-[(methoxy-phenyl-methyl)-carb...)
Affinity DataIC50: 750nMAssay Description:Inhibition of human matrix metalloprotease-2 (MMP-2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50131664(N*4*-Hydroxy-N*1*-{1-[(methoxy-phenyl-methyl)-carb...)
Affinity DataIC50: 930nMAssay Description:Inhibition of Matrix metalloprotease-14More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50131664(N*4*-Hydroxy-N*1*-{1-[(methoxy-phenyl-methyl)-carb...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human Matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed