BDBM50131749 2-[4-Methoxy-3-(4-phenoxy-benzylcarbamoyl)-benzyl]-butyric acid::CHEMBL122070

SMILES CCC(Cc1ccc(OC)c(c1)C(=O)NCc1ccc(Oc2ccccc2)cc1)C(O)=O

InChI Key InChIKey=VYRQBJZRNPNASW-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131749   

TargetPeroxisome proliferator-activated receptor alpha(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131749(2-[4-Methoxy-3-(4-phenoxy-benzylcarbamoyl)-benzyl]...)
Affinity DataEC50:  90nMAssay Description:In vitro effective concentration for agonist activity on human Peroxisome proliferator activated receptor alpha-Gal4 chimeric receptor in transfected...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131749(2-[4-Methoxy-3-(4-phenoxy-benzylcarbamoyl)-benzyl]...)
Affinity DataEC50:  2.40E+3nMAssay Description:Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor gamma expressed in KRP-297 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131749(2-[4-Methoxy-3-(4-phenoxy-benzylcarbamoyl)-benzyl]...)
Affinity DataEC50:  3.00E+3nMAssay Description:Agonist activity on Gal4 chimeric human Peroxisome proliferator activated receptor delta expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed