BDBM50131937 2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-benzo[d][1,2,3]triazin-3-ylmethyl)-cyclopentanecarboxylic acid::CHEMBL126380

SMILES OC(=O)[C@H]1[C@H](Cn2nnc3ccccc3c2=O)CC[C@@H]1Sc1ccc(cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=QKYPFBUZQDJQHX-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50131937   

TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 2.90nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 2.90nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 3.30nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 5nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 63nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 93nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 168nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 235nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 849nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 849nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131937(2-(4'-Chloro-biphenyl-4-ylsulfanyl)-5-(4-oxo-4H-be...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed