BDBM50131940 2-[2-(4'-Chloro-biphenyl-4-yl)-ethylsulfanyl]-5-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-cyclopentanecarboxylic acid::CHEMBL340455

SMILES OC(=O)[C@H]1[C@H](CN2C(=O)c3ccccc3C2=O)CC[C@@H]1SCCc1ccc(cc1)-c1ccc(Cl)cc1

InChI Key InChIKey=AXIUEWMOHLWPSR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50131940   

TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131940(2-[2-(4'-Chloro-biphenyl-4-yl)-ethylsulfanyl]-5-(1...)
Affinity DataIC50: 13nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131940(2-[2-(4'-Chloro-biphenyl-4-yl)-ethylsulfanyl]-5-(1...)
Affinity DataIC50: 45nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131940(2-[2-(4'-Chloro-biphenyl-4-yl)-ethylsulfanyl]-5-(1...)
Affinity DataIC50: 73nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131940(2-[2-(4'-Chloro-biphenyl-4-yl)-ethylsulfanyl]-5-(1...)
Affinity DataIC50: 129nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131940(2-[2-(4'-Chloro-biphenyl-4-yl)-ethylsulfanyl]-5-(1...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed