BDBM50131955 2-(2,4-Dioxo-2H-pyrido[1,2-a][1,3,5]triazin-3-ylmethyl)-5-(4'-methylsulfanyl-biphenyl-4-ylsulfanyl)-cyclopentanecarboxylic acid::CHEMBL339610

SMILES CSc1ccc(cc1)-c1ccc(S[C@H]2CC[C@@H](Cn3c(=O)nc4ccccn4c3=O)[C@@H]2C(O)=O)cc1

InChI Key InChIKey=FWGPCZGIMGDSOM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50131955   

Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131955(2-(2,4-Dioxo-2H-pyrido[1,2-a][1,3,5]triazin-3-ylme...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131955(2-(2,4-Dioxo-2H-pyrido[1,2-a][1,3,5]triazin-3-ylme...)
Affinity DataIC50: 16nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131955(2-(2,4-Dioxo-2H-pyrido[1,2-a][1,3,5]triazin-3-ylme...)
Affinity DataIC50: 195nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131955(2-(2,4-Dioxo-2H-pyrido[1,2-a][1,3,5]triazin-3-ylme...)
Affinity DataIC50: 305nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131955(2-(2,4-Dioxo-2H-pyrido[1,2-a][1,3,5]triazin-3-ylme...)
Affinity DataIC50: 6.30E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed