BDBM50131957 2-(2-Biphenyl-4-yl-ethylsulfanyl)-5-(1,3-dioxo-1,3-dihydro-isoindol-2-ylmethyl)-cyclopentanecarboxylic acid::CHEMBL126923

SMILES OC(=O)[C@H]1[C@H](CN2C(=O)c3ccccc3C2=O)CC[C@@H]1SCCc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=UVAFSUYDCCCUTO-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50131957   

TargetMatrix metalloproteinase-9(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131957(2-(2-Biphenyl-4-yl-ethylsulfanyl)-5-(1,3-dioxo-1,3...)
Affinity DataIC50: 12nMAssay Description:Inhibitory activity against matrix metalloprotease-9 (MMP9)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131957(2-(2-Biphenyl-4-yl-ethylsulfanyl)-5-(1,3-dioxo-1,3...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against matrix metalloprotease-3 (MMP3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131957(2-(2-Biphenyl-4-yl-ethylsulfanyl)-5-(1,3-dioxo-1,3...)
Affinity DataIC50: 46nMAssay Description:Inhibitory activity against matrix metalloprotease-2 (MMP2)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131957(2-(2-Biphenyl-4-yl-ethylsulfanyl)-5-(1,3-dioxo-1,3...)
Affinity DataIC50: 162nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Institut De Recherches Servier

Curated by ChEMBL
LigandPNGBDBM50131957(2-(2-Biphenyl-4-yl-ethylsulfanyl)-5-(1,3-dioxo-1,3...)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibitory activity against matrix metalloprotease-1 (MMP1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed