BDBM50131974 1-Acetyl-4-hydroxy-pyrrolidine-2-carboxylic acid [4-guanidino-1-(thiazole-2-carbonyl)-butyl]-amide; TFA::CHEMBL341083

SMILES CC(=O)N1C[C@H](O)C[C@H]1C(=O)NC(CCCNC(N)=N)C(=O)c1nccs1

InChI Key InChIKey=FOGVEVTZPZCRAO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131974   

TargetSerine protease 1(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131974(1-Acetyl-4-hydroxy-pyrrolidine-2-carboxylic acid [...)
Affinity DataKi:  81nMAssay Description:In vitro inhibition of bovine trypsin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed
TargetTryptase beta-2(Human)
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131974(1-Acetyl-4-hydroxy-pyrrolidine-2-carboxylic acid [...)
Affinity DataKi:  180nMAssay Description:In vitro inhibition of human Tryptase beta.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/29/2012
Entry Details Article
PubMed