BDBM50132160 (2,4-Dichloro-5-methoxy-phenyl)-(7,8-dimethoxy-4a,5,10,10a-tetrahydro-pyrimido[4,5-b]quinolin-4-yl)-amine::CHEMBL102000

SMILES COc1cc(Nc2ncnc3Nc4cc(OC)c(OC)cc4Cc23)c(Cl)cc1Cl

InChI Key InChIKey=OASGPOFUPJRABR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132160   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50132160((2,4-Dichloro-5-methoxy-phenyl)-(7,8-dimethoxy-4a,...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of Src protein tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50132160((2,4-Dichloro-5-methoxy-phenyl)-(7,8-dimethoxy-4a,...)
Affinity DataIC50: 190nMAssay Description:Inhibition of Src protein tyrosine kinase dependent cellular proliferationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed