BDBM50132169 (3-Chloro-phenyl)-(3-isopropyl-1H-pyrazolo[4,3-d]pyrimidin-7-yl)-amine::CHEMBL102846

SMILES CC(C)c1[nH]nc2c(Nc3cccc(Cl)c3)ncnc12

InChI Key InChIKey=RANXSCJPPMGBJW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132169   

LigandPNGBDBM50132169((3-Chloro-phenyl)-(3-isopropyl-1H-pyrazolo[4,3-d]p...)
Affinity DataIC50: 900nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

LigandPNGBDBM50132169((3-Chloro-phenyl)-(3-isopropyl-1H-pyrazolo[4,3-d]p...)
Affinity DataIC50: 900nMAssay Description:Inhibitory concentration against Cyclin-dependent kinase 1-cyclin BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50132169((3-Chloro-phenyl)-(3-isopropyl-1H-pyrazolo[4,3-d]p...)
Affinity DataIC50: 1.84E+4nMAssay Description:In vitro antiproliferative activity against myeloid leukemia K562 cell lineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed