BDBM50132361 2-(4-Methoxy-phenyl)-6-morpholin-4-yl-pyran-4-one::2-(4-methoxyphenyl)-6-morpholino-4H-pyran-4-one::CHEMBL319261

SMILES COc1ccc(cc1)-c1cc(=O)cc(o1)N1CCOCC1

InChI Key InChIKey=QJIHTEXMXZZXDS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132361   

TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50132361(2-(4-methoxyphenyl)-6-morpholino-4H-pyran-4-one | ...)
Affinity DataIC50: 220nMAssay Description:In vitro inhibition of DNA-dependent protein kinase(DNA-PK) from HeLa (human carcinoma) cells.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50132361(2-(4-methoxyphenyl)-6-morpholino-4H-pyran-4-one | ...)
Affinity DataIC50: 220nMAssay Description:Inhibition of DNA-PKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50132361(2-(4-methoxyphenyl)-6-morpholino-4H-pyran-4-one | ...)
Affinity DataIC50: 220nMAssay Description:Inhibition of DNA-PK in HeLa cell nuclear extractsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA-dependent protein kinase catalytic subunit(Human)
University of Newcastle

Curated by ChEMBL
LigandPNGBDBM50132361(2-(4-methoxyphenyl)-6-morpholino-4H-pyran-4-one | ...)
Affinity DataIC50: 220nMAssay Description:Inhibition of DNA-PK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/2/2016
Entry Details Article
PubMed