BDBM50132379 (4-Benzyl-piperazin-1-yl)-(1H-indol-5-yl)-methanone::CHEMBL320069

SMILES O=C(N1CCN(Cc2ccccc2)CC1)c1ccc2[nH]ccc2c1

InChI Key InChIKey=FNQKXOYJSHQLHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132379   

TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50132379((4-Benzyl-piperazin-1-yl)-(1H-indol-5-yl)-methanon...)
Affinity DataIC50: 4.36E+3nMAssay Description:Inhibition of Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Scios

Curated by ChEMBL
LigandPNGBDBM50132379((4-Benzyl-piperazin-1-yl)-(1H-indol-5-yl)-methanon...)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human p38alpha assessed as reduction in [gamma32P]ATP incorporation in to peptide substrate after 40 mins by scintillation counting met...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed