BDBM50132428 5-(Hydroxy-thiophen-2-yl-methyl)-3-[1-(1H-pyrrol-2-yl)-meth-(Z)-ylidene]-1,3-dihydro-indol-2-one::CHEMBL107166

SMILES OC(c1cccs1)c1ccc2NC(=O)\C(=C/c3ccc[nH]3)c2c1

InChI Key InChIKey=DFKYHHCMFRBWRU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132428   

TargetTyrosine-protein kinase JAK3(Human)
Aventis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132428(5-(Hydroxy-thiophen-2-yl-methyl)-3-[1-(1H-pyrrol-2...)
Affinity DataIC50: 190nMAssay Description:Inhibitory activity against Janus Kinase 3 protein tyrosine kinase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed