BDBM50132645 4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(4-isopropyl-cyclohexyl)-piperidin-4-ol::CHEMBL111230

SMILES CC(C)C1CCC(CC1)N1CCC(O)(CC1)c1ccc(Cl)c(c1)C(F)(F)F

InChI Key InChIKey=PWIKMHGXUXTIPG-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132645   

TargetMu-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132645(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(4-isoprop...)
Affinity DataKi:  8nMAssay Description:Antagonistic activity against opioid receptor mu1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNociceptin receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132645(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(4-isoprop...)
Affinity DataKi:  33nMAssay Description:Antagonistic activity against orphan FQ receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Purdue Pharma

Curated by ChEMBL
LigandPNGBDBM50132645(4-(4-Chloro-3-trifluoromethyl-phenyl)-1-(4-isoprop...)
Affinity DataKi:  1.00E+4nMAssay Description:Antagonistic activity against Opioid receptor delta 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed