BDBM50132748 1-(2,6-Difluoro-benzyl)-3-((S)-2-isobutylamino-1-methyl-ethyl)-5-(3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione::CHEMBL112131

SMILES COc1cccc(c1)-c1c(C)n(Cc2c(F)cccc2F)c(=O)n([C@@H](C)CNCC(C)C)c1=O

InChI Key InChIKey=CGNXZWZVWKPVAS-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132748   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132748(1-(2,6-Difluoro-benzyl)-3-((S)-2-isobutylamino-1-m...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed