BDBM50132771 1-(2,6-Difluoro-benzyl)-3-[(R)-2-(3-methoxy-benzylamino)-1-methyl-ethyl]-5-(3-methoxy-phenyl)-6-methyl-1H-pyrimidine-2,4-dione::CHEMBL112559

SMILES COc1cccc(CNC[C@@H](C)n2c(=O)c(c(C)n(Cc3c(F)cccc3F)c2=O)-c2cccc(OC)c2)c1

InChI Key InChIKey=IFTSZJBFFKLIJT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132771   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132771(1-(2,6-Difluoro-benzyl)-3-[(R)-2-(3-methoxy-benzyl...)
Affinity DataKi:  20nMAssay Description:Binding affinity towards human gonadotropin-releasing hormone receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed