BDBM50132797 CHEMBL3634445

SMILES Cc1ccoc1C(=O)Nc1ccc(cc1F)N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=KRAVUTURLMCULG-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50132797   

TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132797(CHEMBL3634445)
Affinity DataIC50: 13nMAssay Description:Positive allosteric modulation of human mGluR1 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132797(CHEMBL3634445)
Affinity DataEC50:  13nMAssay Description:Positive allosteric modulatory activity at human mGlu1 receptor expressed in wild type T-Rex293 cells assessed as increase in glutamate-induced calci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132797(CHEMBL3634445)
Affinity DataEC50:  13nMAssay Description:Positive allosteric modulation of human mGluR1 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50132797(CHEMBL3634445)
Affinity DataEC50: >1.00E+4nMAssay Description:Positive allosteric modulation of human mGluR4 by calcium mobilization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2016
Entry Details Article
PubMed