BDBM50132899 CHEMBL334039::[3-(2,4-Dichloro-phenyl)-2,5-dimethyl-2H-pyrazolo[4,3-b]pyridin-7-yl]-dipropyl-amine

SMILES CCCN(CCC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)n(C)nc12

InChI Key InChIKey=JNRREYMMQMIFGM-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132899   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132899([3-(2,4-Dichloro-phenyl)-2,5-dimethyl-2H-pyrazolo[...)
Affinity DataKi:  4.40nMAssay Description:Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50132899([3-(2,4-Dichloro-phenyl)-2,5-dimethyl-2H-pyrazolo[...)
Affinity DataIC50: 365nMAssay Description:Compound was tested to inhibit Corticotropin releasing factor receptor 1-stimulated c-AMP productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed