BDBM50133360 CHEMBL336217::N-[2-Furan-2-yl-8-(3-methyl-butyl)-8H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-yl]-2-naphthalen-1-yl-acetamide

SMILES CC(C)CCn1cc2c(n1)nc(NC(=O)Cc1cccc3ccccc13)n1nc(nc21)-c1ccco1

InChI Key InChIKey=NVIJFOMRABGFQA-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50133360   

TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50133360(N-[2-Furan-2-yl-8-(3-methyl-butyl)-8H-pyrazolo[4,3...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against NECA stimulated cAMP accumulation in CHO cells expressing human adenosine A2B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50133360(N-[2-Furan-2-yl-8-(3-methyl-butyl)-8H-pyrazolo[4,3...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]DPCPX from human adenosine A2B receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50133360(N-[2-Furan-2-yl-8-(3-methyl-butyl)-8H-pyrazolo[4,3...)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]ZM-241385 from human adenosine A2A receptors expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50133360(N-[2-Furan-2-yl-8-(3-methyl-butyl)-8H-pyrazolo[4,3...)
Affinity DataKi:  142nMAssay Description:Displacement of [3H]DPCPX from human Adenosine A1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50133360(N-[2-Furan-2-yl-8-(3-methyl-butyl)-8H-pyrazolo[4,3...)
Affinity DataKi:  215nMAssay Description:Displacement of [3H]MRE3008-F20 from human A3 receptors expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed