BDBM50133528 3-(4-Aminomethyl-phenyl)-N-cyclopentyl-N-methyl-2-(6,7,8,9-tetrahydro-5H-benzocycloheptene-2-sulfonylamino)-propionamide::CHEMBL119820

SMILES CN(C1CCCC1)C(=O)C(Cc1ccc(CN)cc1)NS(=O)(=O)c1ccc2CCCCCc2c1

InChI Key InChIKey=FRWGOOHSKJKRKQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133528   

TargetProthrombin(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133528(3-(4-Aminomethyl-phenyl)-N-cyclopentyl-N-methyl-2-...)
Affinity DataKi:  3.30nMAssay Description:Inhibitory constant evaluated against thrombin (Factor IIa)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50133528(3-(4-Aminomethyl-phenyl)-N-cyclopentyl-N-methyl-2-...)
Affinity DataKi:  6.30E+3nMAssay Description:Inhibitory constant evaluated against trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed