BDBM50133873 CHEMBL3634020

SMILES C[C@H](NC(=O)CNc1cc(c2c(nn(C)c2n1)-c1ccccc1)C(F)(F)F)c1ccccc1

InChI Key InChIKey=XCGOFXSJHBHNTE-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133873   

TargetOrexin/Hypocretin receptor type 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50133873(CHEMBL3634020)
Affinity DataKi:  357nMAssay Description:Antagonist activity against human orexin 1 receptor after 1 hr by Ca2+ sensitive Fluo4-AM fluorescent dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2016
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50133873(CHEMBL3634020)
Affinity DataKi:  1.14E+3nMAssay Description:Antagonist activity against human orexin 2 receptor after 1 hr by Ca2+ sensitive Fluo4-AM fluorescent dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2016
Entry Details Article
PubMed