BDBM50133880 CHEMBL3634028

SMILES CC(NC(=O)COc1cc(C(F)F)c2c(nn(C)c2n1)-c1ccccc1)c1c(C)nn(C)c1C

InChI Key InChIKey=CESWXAPSIOXDGJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133880   

TargetOrexin receptor type 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50133880(CHEMBL3634028)
Affinity DataKi:  59nMAssay Description:Antagonist activity against human orexin 2 receptor after 1 hr by Ca2+ sensitive Fluo4-AM fluorescent dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2016
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50133880(CHEMBL3634028)
Affinity DataKi:  63nMAssay Description:Antagonist activity against human orexin 1 receptor after 1 hr by Ca2+ sensitive Fluo4-AM fluorescent dye-based FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2016
Entry Details Article
PubMed