BDBM50133891 CHEMBL3634257

SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@@H]1CCNc2ccc(CC3CCc4ccccc34)cc12

InChI Key InChIKey=TTXSDEBRWAKODM-UHFFFAOYSA-N

Data  3 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50133891   

TargetMu-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50133891(CHEMBL3634257)
Affinity DataKi:  0.0500nMAssay Description:Displacement of [3H]diprenorphine from rat mu-opioid receptor expressed in C6 cell membrane for 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50133891(CHEMBL3634257)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]diprenorphine from rat delta-opioid receptor expressed in C6 cell membrane for 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50133891(CHEMBL3634257)
Affinity DataEC50:  9nMAssay Description:Agonist activity at rat mu-opioid receptor expressed in C6 cell membrane assessed as [35S]GTPgammaS binding for 1 hr by liquid scintillation counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50133891(CHEMBL3634257)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]diprenorphine from human kappa-opioid receptor expressed in CHO cell membrane for 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50133891(CHEMBL3634257)
Affinity DataEC50:  180nMAssay Description:Agonist activity at human kappa-opioid receptor expressed in CHO cell membrane assessed as [35S]GTPgammaS binding for 1 hr by liquid scintillation co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2016
Entry Details Article
PubMed