BDBM50134042 CHEMBL1256438

SMILES Cn1cnc(c1)S(=O)(=O)N(CCN(Cc1cncn1C)c1ccc(C#N)c(F)c1)CC1CCN(CC1)c1ncccn1

InChI Key InChIKey=BKJYHXXXORWRAX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134042   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Yale University

Curated by ChEMBL

LigandBDBM50134042(CHEMBL1256438)Copy SMILESCopy InChI

Affinity DataIC50: 230nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/12/2011
Entry Details Article
Copy BDB DOIPubMed
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TargetGeranylgeranyl transferase type-1 subunit beta/Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(Human)
Yale University

Curated by ChEMBL

LigandBDBM50134042(CHEMBL1256438)Copy SMILESCopy InChI

Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
6/12/2011
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL