BDBM50134101 (3aR,10R)-2-Butyl-10-(4-chloro-phenyl)-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione::CHEMBL139048::Cis-2-Butyl-10-(4-chloro-phenyl)-3a,4,9,10-tetrahydro-2,9,10a-triaza-cyclopenta[b]fluorene-1,3-dione

SMILES CCCCn1c(O)c2Cc3c([nH]c4ccccc34)[C@@H](c3ccc(Cl)cc3)n2c1=O

InChI Key InChIKey=LUWMLICOBBYOOA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134101   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50134101(Cis-2-Butyl-10-(4-chloro-phenyl)-3a,4,9,10-tetrahy...)
Affinity DataIC50: 50nMAssay Description:Inhibitory activity against bovine PDE5 (phosphodiesterase-5).More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Universidade Federal De Lavras-Ufla

Curated by ChEMBL
LigandPNGBDBM50134101(Cis-2-Butyl-10-(4-chloro-phenyl)-3a,4,9,10-tetrahy...)
Affinity DataIC50: 50nMAssay Description:Inhibition of PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed