BDBM50134123 (6R,7R)-10-Butyl-6-(4-methoxy-phenyl)-5,6,9,10,11a,12-hexahydro-indolo[3,2-b]quinolizine-8,11-dione::CHEMBL138504::CHEMBL139771

SMILES CCCCn1c(O)c2Cc3c([nH]c4ccccc34)C(c3ccc(OC)cc3)n2c1=O

InChI Key InChIKey=GKNMKFGNESPSPX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50134123   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50134123(CHEMBL138504 | CHEMBL139771 | (6R,7R)-10-Butyl-6-(...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against bovine phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Bovine)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50134123(CHEMBL138504 | CHEMBL139771 | (6R,7R)-10-Butyl-6-(...)
Affinity DataIC50: 8nMAssay Description:In vitro inhibitory activity against bovine phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Univ. Grenoble Alpes

Curated by ChEMBL
LigandPNGBDBM50134123(CHEMBL138504 | CHEMBL139771 | (6R,7R)-10-Butyl-6-(...)
Affinity DataIC50: 3nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed