BDBM50134181 CHEMBL3735451

SMILES Clc1cccc(\C=C\C(=O)c2ccc[nH]2)c1

InChI Key InChIKey=YAKJTWICTNXZIR-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50134181   

TargetAmine oxidase [flavin-containing] A(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50134181(CHEMBL3735451)
Affinity DataIC50: 1.43E+5nMAssay Description:Inhibition of human MAO-A expressed in baculovirus infected BT1 cells microsome fraction by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2017
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
North-West University

Curated by ChEMBL
LigandPNGBDBM50134181(CHEMBL3735451)
Affinity DataIC50: 3.27E+3nMAssay Description:Inhibition of human MAO-B expressed in baculovirus infected BT1 cells microsome fraction by fluorescence spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50134181(CHEMBL3735451)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP3A4 bound to yeast microsomal membrane using dibenzylfluorescein as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50134181(CHEMBL3735451)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human CYP2D6 bound to yeast microsomal membrane using 7-ethoxy-methyloxy-3-cyanocoumarin as substrate after 10 mins by fluorescence ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50134181(CHEMBL3735451)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C19 bound to yeast microsomal membrane using 3-cyano-7-ethoxycoumarin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50134181(CHEMBL3735451)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human CYP1A2 bound to yeast microsomal membrane using 3-cyano-7-ethoxycoumarin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50134181(CHEMBL3735451)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C9 bound to yeast microsomal membrane using 3-cyano-7-ethoxycoumarin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetCytochrome P450 1A1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50134181(CHEMBL3735451)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of human CYP1A1 bound to yeast microsomal membrane using 7-ethoxyresorufin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed
TargetCytochrome P450 1B1(Human)
De Montfort University

Curated by ChEMBL
LigandPNGBDBM50134181(CHEMBL3735451)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human CYP1B1 bound to yeast microsomal membrane using 7-ethoxyresorufin as substrate after 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2020
Entry Details Article
PubMed