BDBM50134324 CHEMBL3747019

SMILES CN1CCn2nc(Nc3cc(n[nH]c3=O)-c3ccc(C)c(NC(=O)c4cc5ccccc5s4)c3F)cc2C1

InChI Key InChIKey=OHZNHWDXCHGYRT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134324   

TargetTyrosine-protein kinase BTK(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50134324(CHEMBL3747019)
Affinity DataIC50: 11nMAssay Description:Inhibition of BTK (unknown origin) by Lanthascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetTyrosine-protein kinase BTK(Mouse)
Genentech

Curated by ChEMBL
LigandPNGBDBM50134324(CHEMBL3747019)
Affinity DataIC50: 200nMAssay Description:Inhibition of BTK in Balb/c mouse B cells assessed as inhibition of anti-IgM-stimulated CD86 expression by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed