BDBM50134393 CHEMBL3746464

SMILES COc1cccc(Nc2c(cnc3c(C)c(nn23)S(=O)(=O)c2ccccc2)C(N)=O)c1

InChI Key InChIKey=RRKOMNZJZUGUEB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134393   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134393(CHEMBL3746464)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant PDE4B1 expressed in insect Sf9 cells by fluorescence capillary-electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Sanofi Research Center

Curated by ChEMBL
LigandPNGBDBM50134393(CHEMBL3746464)
Affinity DataIC50: 243nMAssay Description:Inhibition of PDE4 in human SHSY-5Y cells assessed as suppression of cAMP hydrolysis by HTRF assay in presence of dye d2 labelled cAMPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed