BDBM50134446 CHEMBL3747597

SMILES Fc1cnc(nc1)N1CCn2nc(COc3ccccc3)cc2C1=O

InChI Key InChIKey=NAXOZSWVZBCFEI-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134446   

TargetMetabotropic glutamate receptor 5(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50134446(CHEMBL3747597)
Affinity DataEC50:  759nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50134446(CHEMBL3747597)
Affinity DataEC50:  760nMAssay Description:Positive allosteric modulation of human mGlu5 expressed in HEK293 cells assessed as glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed