BDBM50134794 CHEMBL3746637

SMILES CC(C)(C)OC(=O)N1C[C@H](Nc2nc3cc(F)ccc3[nH]2)[C@H](C1)OC(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=ONXOLONSBJTOEF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50134794   

TargetBeta-secretase 1(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50134794(CHEMBL3746637)
Affinity DataIC50: 50nMAssay Description:Inhibition of BACE1 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetCathepsin D(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50134794(CHEMBL3746637)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50134794(CHEMBL3746637)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed