BDBM50134818 CHEMBL3746261

SMILES CC(C)c1ccc(cc1)C(=O)O[C@H]1CN(C[C@@H]1Nc1nc2cc(F)ccc2[nH]1)C(=O)OC(C)(C)C

InChI Key InChIKey=OWXJEEIJHWOZKB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50134818   

TargetBeta-secretase 1(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50134818(CHEMBL3746261)
Affinity DataIC50: 70nMAssay Description:Inhibition of BACE1 (unknown origin) by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetBeta-secretase 2(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50134818(CHEMBL3746261)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of BACE2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed
TargetCathepsin D(Human)
Korea University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50134818(CHEMBL3746261)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of cathepsin D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMed