BDBM50135134 6-Phenylaminomethyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL358003

SMILES Nc1nc(N)c2cc(CNc3ccccc3)cnc2n1

InChI Key InChIKey=AURBMPJKJCBLSU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135134   

TargetDihydrofolate reductase(Escherichia coli (strain K12))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135134(6-Phenylaminomethyl-pyrido[2,3-d]pyrimidine-2,4-di...)
Affinity DataIC50: 270nMAssay Description:Inhibition of dihydrofolate reductase from Toxoplasma gondii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli (strain K12))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135134(6-Phenylaminomethyl-pyrido[2,3-d]pyrimidine-2,4-di...)
Affinity DataIC50: 2.22E+3nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDihydrofolate reductase(Rat)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50135134(6-Phenylaminomethyl-pyrido[2,3-d]pyrimidine-2,4-di...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of dihydrofolate reductase from rat liver.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed