BDBM50135189 CHEMBL3741064

SMILES COc1cc(cc2c1nc(C)c1c(C)nc(-c3ccnc(F)c3)n21)-c1ccnc(F)c1

InChI Key InChIKey=SMBDWRLHTIVDJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135189   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Institute of Radiopharmaceutical Cancer Research

Curated by ChEMBL
LigandPNGBDBM50135189(CHEMBL3741064)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of human recombinant PDE10A1 expressed in baculovirus infected insect SF21 cells using [3H]cAMP as substrate after 30 mins by scintillatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2017
Entry Details Article
PubMed