BDBM50135308 1-(2-Chloro-6-ethyl-phenyl)-6-(4-fluoro-phenylsulfanyl)-3,4-dihydro-1H-pyrido[3,2-d]pyrimidin-2-one::CHEMBL129704

SMILES CCc1cccc(Cl)c1N1C(=O)NCc2nc(Sc3ccc(F)cc3)ccc12

InChI Key InChIKey=RALFBQAGUPRMMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135308   

TargetMitogen-activated protein kinase 14(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135308(1-(2-Chloro-6-ethyl-phenyl)-6-(4-fluoro-phenylsulf...)
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50135308(1-(2-Chloro-6-ethyl-phenyl)-6-(4-fluoro-phenylsulf...)
Affinity DataIC50: 200nMAssay Description:Inhibitory activity against mitogen-activated protein kinase p38 betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed