BDBM50135376 5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(2,3-dimethyl-3H-imidazol-4-yl)-methoxymethyl]-1-methyl-2-oxo-1,2-dihydro-pyridine-3-carbonitrile::CHEMBL131116

SMILES Cc1ncc(C(OCc2c(cc(C#N)c(=O)n2C)-c2cccc(Cl)c2)c2ccc(cc2)C#N)n1C

InChI Key InChIKey=JGXPXXUUXXPAIZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135376   

LigandPNGBDBM50135376(5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(2,3-dimet...)
Affinity DataIC50: 5.30nMAssay Description:In vitro inhibitory activity against farnesyltransferase (FT)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50135376(5-(3-Chloro-phenyl)-6-[(4-cyano-phenyl)-(2,3-dimet...)
Affinity DataIC50: 900nMAssay Description:In vitro inhibitory activity against Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed