BDBM50135402 CHEMBL130971::[4-Ethyl-5-(2,4,6-trimethyl-phenylcarbamoyl)-thiazol-2-yl]-carbamic acid tert-butyl ester

SMILES CCc1nc(NC(=O)OC(C)(C)C)sc1C(=O)Nc1c(C)cc(C)cc1C

InChI Key InChIKey=HOLBGXPLWKDXJO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135402   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135402([4-Ethyl-5-(2,4,6-trimethyl-phenylcarbamoyl)-thiaz...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CD3/CD28 T-cell proliferation assay in PBL (peripheral blood lymphocytes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed