BDBM50135403 CHEMBL130320::[5-(2,4,6-Trimethyl-phenylcarbamoyl)-thiazol-2-yl]-carbamic acid tert-butyl ester

SMILES Cc1cc(C)c(NC(=O)c2cnc(NC(=O)OC(C)(C)C)s2)c(C)c1

InChI Key InChIKey=GAYHCDONHMTTTE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50135403   

TargetTyrosine-protein kinase Lck(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135403([5-(2,4,6-Trimethyl-phenylcarbamoyl)-thiazol-2-yl]...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CD3/CD28 T-cell proliferation assay in PBL (peripheral blood lymphocytes)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed