BDBM50135636 (S)-2-[(S)-2-(5-Cyano-isoxazole-3-carbonyl)-pyrrolidine-1-carbonyl]-pyrrolidine-1-carboxylic acid benzyl ester::CHEMBL100213

SMILES O=C(OCc1ccccc1)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)c1cc(on1)C#N

InChI Key InChIKey=JMJJLRQHUQIIAJ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135636   

TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135636((S)-2-[(S)-2-(5-Cyano-isoxazole-3-carbonyl)-pyrrol...)
Affinity DataKi:  7.5nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (Tc80) in Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase(Human)
University of Antwerp

Curated by ChEMBL
LigandPNGBDBM50135636((S)-2-[(S)-2-(5-Cyano-isoxazole-3-carbonyl)-pyrrol...)
Affinity DataKi:  38nMAssay Description:In vitro inhibitory activity determined against prolyl oligopeptidase (PO) in human; Moderately activeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed