BDBM50135841 (4-methylthiazol-2-ylamino)methylenediphosphonic acid::(Bis-phosphono-methyl)-(4-methyl-thiazol-2-yl)-ammonium::CHEMBL293116::[(4-Methyl-thiazol-2-ylamino)-phosphono-methyl]-phosphonic acid

SMILES Cc1csc(NC(P(O)(O)=O)P(O)(O)=O)n1

InChI Key InChIKey=WPRZJIVPPUKPKR-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50135841   

TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135841((4-methylthiazol-2-ylamino)methylenediphosphonic a...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135841((4-methylthiazol-2-ylamino)methylenediphosphonic a...)
Affinity DataIC50: 347nMAssay Description:Negative logarithm of inhibitory concentration against bone resorptionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135841((4-methylthiazol-2-ylamino)methylenediphosphonic a...)
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibitory activity against farnesyl Pyrophosphate Synthase expressed as #NAME (M)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetFarnesyl pyrophosphate synthase(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50135841((4-methylthiazol-2-ylamino)methylenediphosphonic a...)
Affinity DataKi:  180nMAssay Description:Binding affinity towards farnesyl Pyrophosphate Synthase using [14C]- isopentenyl pyrophosphate as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed