BDBM50135955 2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyrazole-3-carboxylic acid (3-fluoro-2'-sulfamoyl-biphenyl-4-yl)-amide::CHEMBL149260

SMILES COc1ccc(cc1)-n1nc(cc1C(=O)Nc1ccc(cc1F)-c1ccccc1S(N)(=O)=O)C(F)(F)F

InChI Key InChIKey=AREHOUGDCWGZMH-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135955   

TargetCoagulation factor X(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135955(2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyrazole...)
Affinity DataKi:  4.20nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProthrombin(Human)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135955(2-(4-Methoxy-phenyl)-5-trifluoromethyl-2H-pyrazole...)
Affinity DataKi: >2.10E+4nMAssay Description:In vitro for inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed