BDBM50136235 CHEMBL3754346

SMILES Nc1ncnc2n(Cc3ccccc3)nc(-c3cc(on3)C3CC3)c12

InChI Key InChIKey=OWROSELBAIWMET-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50136235   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136235(CHEMBL3754346)
Affinity DataIC50: 74nMAssay Description:Inhibition of human wild type RET by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Korea Institute of Science & Technology (Kist)

Curated by ChEMBL
LigandPNGBDBM50136235(CHEMBL3754346)
Affinity DataIC50: 557nMAssay Description:Inhibition of human Ret V804M mutant by radiometric assay in presence of [gamma-33P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2017
Entry Details Article
PubMed