BDBM50136378 4-(3-Chloro-phenyl)-6-[(4-chloro-phenyl)-hydroxy-(3-methyl-3H-imidazol-4-yl)-methyl]-1H-quinolin-2-one::CHEMBL344703

SMILES Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2[nH]c(=O)cc(-c3cccc(Cl)c3)c2c1

InChI Key InChIKey=YLWZTUJNSOKAOC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50136378   

TargetProtein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha(Human)
Medicinal Chemistry Department Johnson & Johnson Pharmaceutical Research & Development (J&Jprd)

Curated by ChEMBL
LigandPNGBDBM50136378(4-(3-Chloro-phenyl)-6-[(4-chloro-phenyl)-hydroxy-(...)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]FPP incorporation into biotinylated lamin B peptide by farnesyl transferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed